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It had all the elements of the kind of fraud we are n the lookout for today, but back then were essentially unheard of – ghostwriting [Sally Laden], corrupt KOLs [Charles Nemeroff], flooding of the literature, etc. The discontinuation symptoms [withdrawal] was first reported in 1994, and in a wave of articles in 1995, but didn’t really get appropriate attention until the 2001 report by Haddad: Discontinuation symptoms are recognised with tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin reuptake inhibitors (SSRIs) and miscellaneous antidepressants. A wide variety of symptoms have been described, differing somewhat between antidepressant classes, and several symptom clusters or discontinuation syndromes appear to exist. A common feature is onset within a few days of stopping the antidepressant or, less commonly, reducing the dosage. 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