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    Mirtazapine and citalopram are both antidepressant drugs that influence the mood-elevating chemical serotonin in the brain. They are generally prescribed for the treatment of major depressive disorder, but citalopram may also be used to treat some anxiety disorders. These medicines should not be combined except under the orders of a physician. Although the precise effects of combining mirtazapine and citalopram have not been studied extensively, any two drugs that effect serotonin levels have the potential to cause serotonin syndrome. The risks of other, less serious side effects may also be increased. Since the two drugs have generally very similar effects, it is often better to increase the dosage of one rather than combining them together. Citalopram, sold under the brand name Celexa®, is a selective serotonin re-uptake inhibitor (SSRI) drug, meaning that it keeps the neurotransmitter serotonin from being reabsorbed into the bloodstream as quickly. Citalopram is an antidepressant which enhances a level of serotonin in the neural synapses of the central nervous system and improves an emotional state. A medical ingredient Citalopram is often used as a base to create antidepressant. This medicine has shown a high efficiency in the treatment of the depression of any severity and differed by good intolerance. An intensity of the side effects of Citalopram can be controlled by means of the dose adjustment, and therefore the depression treatment goes without negative symptoms during the properly selected dose. Citalopram blocks a reuptake of serotonin, so that the level of this neurotransmitter is increased. Serotonin has a broad action to the human body but its main task is to improve a psychoemotional health. A medical effect of Citalopram achieves maximum in about 2 weeks and is kept during the prolonged use.

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