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By decreasing production of liver glucose and improving sensitivity to insulin, Metformin reduces high blood sugar and health complications resulting from type 2 diabetes. It also enhances effectiveness of the body’s utilization of existing glucose to support minimization of intestinal absorption of blood glucose. Instead of being metabolized in the stomach, alcohol directly enters the bloodstream where it quickly travels to the liver to be assimilated by the body. When someone drinks alcohol faster than it takes for the liver to metabolize alcohol, any excess alcohol saturates body tissues, especially the brain. Processing a bottleneck of alcohol means the liver has no choice but to release less glucose and dysregulate blood sugar levels. In addition, many alcoholic drinks contain a lot of sugar that may contribute to health conditions promoting type 2 diabetes, such as obesity and having prediabetes. Doctors have long faced a paradox when advising their patients with type 2 diabetes on drinking alcohol. Moderate drinking has been shown to reduce the risk of heart disease, which would benefit people with diabetes who are at increased risk of the disease. Yet, people with diabetes have traditionally been advised to reduce their alcohol consumption to help better control their glucose levels. The study randomly assigned 224 patients with controlled type 2 diabetes to have either mineral water, white wine or red wine (about a 5-ounce serving of wine) with dinner every night for two years. All patients were following a healthy Mediterranean diet with no calorie restrictions. Researchers found that red-wine drinkers had a modest improvement in high-density lipoproteins (HDL), the good cholesterol, and also had improved apolipoprotein A1, a component of HDL. Those who drank red or white wine also saw modest improvements in glucose metabolism. 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