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    Both the Phenergan tablets and the Phenergan Elixir contains the active ingredient Promethazine, Promethazine is a type of medicine named a sedating antihistamine of which works by preventing the actions and effects of histamine. Histamine is produced by the body as a defence and causes symptoms of an allergic reaction such as sneezing, rashes, sore eyes, nasal congestion. Promethazine blocks the histamine receptors in the area of the brain thus preventing the messages causing the symptoms. Promethazine (Phenergan, Sominex) is an antihistamine sometimes used as a sleeping pill. It's available to buy without a prescription from a doctor. It is also an ingredient in some over-the-counter cold and flu medicines, such as Night Nurse. You can find detailed information about promethazine in the official Patient Information Leaflet (PIL), including what it's for, how to take it, possible side effects and safety information. This leaflet should come with your medication (usually inside the box). All PILs for drugs containining promethazine are available online on the electronic Medicines Compendium (e MC). If a drug can come in different forms (such as tablets or liquid), there may be a separate PIL for each one.

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